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				<p class="content-title">Impact of New Science</p>
				
				<ol type="I" class="paragraph">
					<li><strong>Personalized medicine</strong></li>					
					<p class="paragraph">Personalized medicine is a method of molecular analysis use to develop health care services and treatment for a specific individual
					in order to maximize health results. Personalized medicine assures to change healthcare by having possibilities of improving health 
					outcomes and make healthcare more cost-effective. An example of personalized medicine is genotyping, wherein an individual’s DNA sequence 
					is examined by biological assay. </p>	
					<p class="paragraph">Benefits of Personalized Medicine:</p>
					<ul class="paragraph disc">
						<li>Better diagnoses and earlier interventions</li>
						<li>More efficient drug development</li>
						<li>More effective therapies</li>
					</ul></br>
					
					<li><strong>Molecular diagnostics</strong></li>					
					<p class="paragraph">Molecular Diagnostics is a method of diagnostic testing that studies the molecular mechanisms of an individual patient’s disease 
					to provide an effective treatment for many diseases in the future. Molecular Diagnostic covers a role in personalized medicine in 
					the following aspects:</p>
					<ul class="paragraph disc">
						<li>Early detection and selection of appropriate treatment determined to be safe and effective on the basis of molecular diagnostics</li>
						<li>Integration of molecular diagnostics with therapeutics</li>
						<li>Monitoring therapy as well as determining prognosis</li>
					</ul></br>
					<p class="paragraph">Two important components of personalized medicine:</p>
					<ol class="paragraph">
						<li><strong><i>Pharmacogenetics</i></strong> - the study of genetic variation resulting to varying responses to drugs.</li>
						<li><strong><i>Pharmacogenomics</i></strong> - concerns with the broader application of genomic technologies in discovering new drugs
						and characterizing older drugs.</li>
					</ol></br>
					<p class="paragraph">Two types of tests relevant to personalized medicine:</p>
					<ol class="paragraph">
						<li><strong><i>Pharmacogenomic test</i></strong> - concerns with testing the whole genome single nucleotide polymorphism (SNP) maps 
						and haplotype markers, alterations in gene expression, or inactivation that may be correlated with pharmacological function and 
						therapeutic response.</li>
						<li><strong><i>Pharmacogenetic test</i></strong> – concerns with  testing the interindividual variations in DNA sequence related to 
						drug absorption and disposition (pharmacokinetics), including polymorphic variations in genes that encode the functions of transporters,
						metabolizing enzymes, receptors, and other proteins.</li>
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